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I found a really cool coronavirus illustration that led me to learn about viral attachment and entry.
To learn more about this topic, start your googling with these keywords:
Virus: a submicroscopic infectious agent that replicates only inside the living cells of an organism. The study of viruses is known as virology.
Virion: a complete virus particle, and consists of nucleic acid surrounded by a protective coat of protein called a capsid.
Coronaviruses: a group of related RNA viruses that cause diseases in mammals and birds. In humans and birds, they cause respiratory tract infections that can range from mild to lethal and include some cases of the common cold, SARS, MERS, and COVID-19.
SARS-CoV-2: the virus that causes coronavirus disease 2019 (COVID-19), the respiratory illness responsible for the COVID-19 pandemic.
Class I fusion proteins: resemble influenza virus hemagglutinin in their structure. Post-fusion, the active site has a trimer of α-helical coiled-coils
Proteins featured in this video:
8211; SARS-CoV-2 Spike (S) Protein
8211; Heparan Sulfate Proteoglycan (HSPG) (Syndecan-4, especifically)
8211; Angiotensin-converting enzyme 2 (ACE2)
8211; Transmembrane protease, serine 2 (TMPRSS2)
If you liked this week’s video, you might also like:
Coronaviruses 101: Focus on Molecular Virology by Britt Glaunsinger
Virology Lectures 2021: Attachment and entry by Vincent Racaniello
Building a visual consensus model of the SARS-CoV-2 life cycle
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SARS-CoV-2 Fusion, 2020 8211; Illustration by David S. Goodsell, RCSB Protein Data Bank; doi: 10.2210/rcsb_pdb/goodsell-gallery-026
Coronavirus outbreak (covid 19) explained through 3D Medical Animation 8211; Video by scientificanimations.com
Coronavirus, Explained: This Pandemic 8211; Video by Netflix
How the Coronavirus Hijacks Your Cells 8211; Video by Bloomberg Quicktake
Ink Drop/Drip in water 8211; Video by CyberWebFX
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